laminae
delivering on biocomputing's true promise. (very) early stage.
bioeng. @ umd · synbio · protein engineering · biocomputing
broadly, i'm interested in decoding the rules governing self-assembly of multicellular structures (organs & organisms), and using those rules to build de novo systems for human health, augmentation, and advancement. these could be improved organs, self-assembling neural circuits, intelligent microbots, or something else entirely.
however, i am a serial builder, and my interests are highly varied from coffee to cervical cancer ;) take a look below!
delivering on biocomputing's true promise. (very) early stage.
free coffee + community every friday at UMD. 1,000+ members, $30K/yr, major collabs, 250–500 students/event. NPO coming soon :)
working on [ ;D ].
designed and screened 10⁹-candidate phage display libraries. built protein docking/scoring pipelines, characterized anti-idiotype antibodies, and initiated the company's first synbio protein engineering campaign. poster here.
led development of toehold riboswitches for miRNA-based cervical dysplasia detection. validated in vivo and cell-free. led human practices work. assisted on computational work and riboswitch design tool. gold medal, Paris World Expo of Synthetic Biology 2024. best poster, UMD/JHU BMES 2024.
project wiki here (contains all results); poster here.
engineered a low-cost cell-free system expressing custom biosensors and cytotoxic proteins. mentored 20+ students; served on FIRE student leadership council. posters here and here.
bringing the startup-spawning swag of software hackathons to biotech. reach out if interested in helping out.
proposed replacing the proteolytic switch in hevin (a bifunctional protein that both assembles & eliminates thalamocortical synapses) with a photonic one.
designed phocl2f-hevin photocleavable construct. used alphafold & computational analysis to select sites for affinity maturation of the tlr4-binding fragment via yeast display. first concept for optogenetic control of the hevin-mediated developmental pruning pathway.
proposal document here; presentation here.
mentoring team 23396 (2026 TN state inspire award winners) & team 7149 (too many awards to list).
publication writing and non-technical / program sustainability strategy.